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Epidemiology and pathophysiology of Constipation.

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eMediNexus    31 July 2018

The purpose of a new article published by the Stat Pearls reported that functional constipation (FC) is a common condition in children; its prevalence is about 29.6% worldwide. The authors discussed that a majority of the children with FC do not have an etiological factor and one third continue to have problems beyond adolescence. Meanwhile, up to 84% of functionally constipated children suffer from fecal incontinence while more than one-third of children present with behavioral problems, primary or secondary due to constipation. It was further stated that the pathophysiology underlying functional constipation is multifactorial and not well understood. Factors that may contribute to functional constipation include pain, fever, dehydration, dietary and fluid intake, psychological issues, toilet training, medicines, and family history of constipation. The authors described that chronic idiopathic constipation is characterized by a lack of periodicity in defecating and difficulty or pain during defecation without an identifiable organic cause, such as physiological, anatomical, radiological or histological. Despite having a high incidence in children, the underlying cause for chronic constipation is identified in less 5% of the cases.

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