The goal of a new study published in Rheumatology International was to clarify whether Henoch-Schönlein purpura (HSP) predisposes children to functional gastrointestinal disorders (FGIDs). This study recruited 74 children with HSP diagnosed at least 6 months earlier, and 78 healthy controls. Patients with warning signs for organic gastrointestinal (GI) disorders were excluded; Rome IV criteria were utilized for FGIDs diagnosis. Frequencies of FGIDs were compared between HSP patients and healthy subjects. Parameters including age, abdominal pain, arthralgia, bloody stool, renal involvement and treatment with corticosteroids, and laboratory results at HSP diagnosis, such as erythrocyte sedimentation rate, C-reactive protein, hemoglobin, leukocytes and platelet counts were examined for patients with and without FGIDs. The results revealed that frequencies of FGIDs and irritable bowel syndrome (IBS) were 35.1% and 10.8% in HSP patients and 19.2% and 2.6% in healthy controls, respectively. While disease characteristics and laboratory parameters at disease onset were similar between HSP patients with and without FGIDs. Moreover, FGIDs rate, especially, IBS was statistically higher in HSP patients. Therefore, it was hypothesized that children with preceding HSP may be predisposed to FGIDs. It was stated that physicians should examine HSP patients with ongoing abdominal pain for signs of FGIDs, to facilitate prevention of this comorbidity with dietary and psychologic measures.