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Comparison and analysis of statins drug use in the treatment of diastolic dysfunction in patients.

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eMediNexus    13 September 2018

A new article published in the Pakistan Journal of Pharmaceutical Sciences stated that statins have multiple antilipidemic effects, such as anti-inflammatory, anti-oxidation and anti-arteriosclerosis, which are beneficial to improve cardiac function. It was reported that statins can effectively improve left ventricular remodeling and protect ventricular diastolic function. The present article described a study, which evaluated the effects of statin therapy on diastolic function, brain natriuretic peptide (BNP) level, and exercise tolerance in patients with diastolic dysfunction. The results showed that after atorvastatin treatment, the exercise SBP decreased in the treatment group, which significantly varied from that before treatment and the control group. This study demonstrated that atorvastatin can treat patients with diastolic dysfunction and exercise hypertension by lowering blood pressure and reducing exercise SBP, rendering an anti-inflammatory effect, and improving vascular endothelial function.

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