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Lipid profile pattern in pediatric overweight population with or without NAFLD.

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eMediNexus    31 October 2017

A new study published in the Romanian Journal of Internal Medicine assessed the lipid profile pattern of pediatric overweight and or obese patients with Non Alcoholic Fatty Liver Disease NAFLD in relation to International Diabetes Federation IDF Consensus Criteria for Metabolic Syndrome MetS. This cross sectional preliminary study enrolled 45 consecutive pediatric overweight or obese children aged from 3 to 18 years. In these pediatric patients standardized measurement of blood pressure and anthropometric parameters were performed. It was observed that the prevalence of MetS was 44.4 . On the other hand 46.7 patients had NAFLD while MetS patients had a higher risk for NAFLD. In addition patients with positive familial history of type 2 diabetes had 6.61 fold higher risk for NAFLD. A subgroup analysis in patients under ten years of age revealed that those who had both NAFLD and MetS met the hyper triglyceride criterion more frequently. Furthermore triglyceride levels independently associated with NAFLD. Hence it was concluded that NAFLD obese patients had higher prevalence of MetS higher body mass index BMI and specific lipid profile pattern. It was stated that triglyceride levels independently associated with NAFLD. Hence an early triglyceride testing even below the age of ten was recommended in selected patients.

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