Low-Dose Polyethylene Glycol plus Electrolytes for Adults with Chronic Functional Constipation.
The goal of a study published in Clinical Drug Investigation compared the efficacy and safety of polyethylene glycol 3350 plus electrolytes (PEG+E) to that of ispaghula husk (psyllium) in the treatment of constipation. This randomized, controlled, open-label, parallel-group trial included adults with chronic functional constipation. Group 1 comprising 63 patients received PEG+E 13.8g/sachet dissolved in water twice daily for 2 weeks, while group 2 formed by an equal number of patien
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