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An experimental vaccine - S100A9 - may one day be able to replace oral blood thinners to reduce the risk of secondary strokes caused by blood clots, without increasing the risk of serious bleeding or triggering an autoimmune response, according to new research in the journal Hypertension, reported online Oct. 29, 2018. The vaccine was found to be as safe and effective as one of the most widely used oral blood thinners currently used to reduce clotting risk.