A new study published in the Journal of Affective Disorders examined the effectiveness and safety of non-pharmacological treatment options – complementary medicines and therapies, on depression and anxiety during pregnancy. This study entailed a search from CENTRAL, EMBASE, and PubMed databases for randomized controlled trials (RCTs) comparing complementary therapies and medicines to a control, for pregnant women with depression or anxiety. The primary outcome measure was antenatal depression or anxiety. Overall, 20 RCTs containing 1,092 women were selected. The results displayed some evidence of reduced antenatal depression from three of the modalities. Acupuncture reduced the number of women diagnosed with antenatal depression and massage reduced the severity of antenatal depression in one trial including 149 women. Additionally, a trial of bright light therapy demonstrated reduced antenatal depression in 27 pregnant women. However, an evidence of a reduction in depression and anxiety from relaxation, yoga, mindfulness, and fish oils could not be found. In conclusion, it was stated that despite a few high quality RCTs of complementary medicines and therapies examining the effect on anxiety and depression during pregnancy, massage, acupuncture, and bright light therapy has shown to reduce antenatal depression. High quality and larger studies that include postnatal follow up and maternal and neonatal outcomes were proposed.