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Complementary medicines and therapies - Impact on maternal anxiety and depression in pregnancy

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eMediNexus Editorial    09 January 2019

Depression and anxiety are commonly seen during the antenatal and postnatal periods. They are known to significantly affect the woman and the fetus. Pregnant women often use complementary medicines and therapies to manage these conditions. A systematic review and meta-analysis published recently in the Journal of Affective Disorders assessed the effectiveness and safety of these modalities on depression and anxiety during pregnancy. Researchers searched CENTRAL, EMBASE and PubMed databases for randomized controlled trials comparing complementary therapies and medicines to a control among pregnant women with depression or anxiety. The primary outcome measure was antenatal depression or anxiety.In all, 20 randomized controlled trials involving 1092 women were included. Some evidence of reduced antenatal depression was noted from three modalities. Acupuncture reduced the number of women diagnosed with antenatal depression (RR 1.68, 95% CI 1.06–2.66, 1 trial). Massage was found to reduce the severity of antenatal depression in one trial of 149 women (SMD −0.73, 95%CI −1.07–−0.39). A small trial of bright light therapy showed reduced antenatal depression (RR 4.80, 95% CI −8.39–−1.21, 27 women).Therefore, acupuncture, massage and bright light therapy may reduce antenatal depression. High quality and larger studies that include postnatal follow-up and maternal and neonatal outcomes are needed.

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