• ART alone cannot be seen in isolation, ensure regular supply of ART.
• ART classes of new drugs:

o  NNRTI: delaviridine, relpivirine

o  PI: tipranavir, fosamprenavir

o  Biologics: ibalizumab

o  Integrase inhibitor: cobiseistat.

• WHO guidelines 2018 DTG in first line RAL as an alternate, PEP three drugs.
• Key factors to structure ART CD4, viral load and co-infections.