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Oral Itraconazole for Treatment of Infantile Hemangiomas: Updated Clinical and Mechanism Research

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Dr Yuping Ran, Chenglu, China    23 January 2019

  • The clinical efficacy of oral itraconazole is 71.05%.
  • It may cause mild, reversible diarrhea.
  • Down regulation of P13-AKT-mTOR and Hedgehog signalling pathways, inhibition of hemangioma cell growth.
  • Induces hemangioma endothelial cells autophagy and apoptosis.

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